Gene name
Plxnb2 (KIAA0315)
Experiment(s)
For this entry:
PLXB2_HUMAN (Plxnb2)
Species | Homo sapiens |
---|---|
Localization | Basolateral plasma membrane |
Reference |
Chin AR,Yan W,Cao M,Liu X,Wang SE (2018) Polarized Secretion of Extracellular Vesicles by Mammary Epithelia., J Mammary Gland Biol Neoplasia, 23, 165-176. [PubMed] [DOI] |
Evidence level | Large-scale proteomics |
Organ | Mammary gland |
Cell | MCF10A cells (acinar cells) |
Notes | Detected in the polarized exosome fraction |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start | End | Localisation |
---|---|---|
1 | 19 | Signal peptide |
20 | 1197 | Extracellular |
1198 | 1219 | Membrane |
1220 | 1838 | Cytoplasmic |
Phosphorylation
Position | Resource |
---|---|
126 | 36420134 |
200 | 55368065 |
419 | 3436782 |
452 | 18013956 |
650 | 55368069 |
1124 | 18013953 |
1224 | 23133344 |
1231 | 23133353 |
1244 | 12738854 |
1317 | 55368073 |
1320 | 23133347 |
1325 | 23133350 |
1327 | 17544699 |
1349 | 3664989 |
1410 | 3562596 |
1412 | 3662549 |
1422 | 3562601 |
1499 | 23133356 |
1548 | 50479811 |
1570 | 4719529 |
1614 | 11129568 |
1621 | 23133359 |
1623 | 11129572 |
1627 | 11129576 |
1756 | 55368077 |
Glycosylation
Family and domain data
Database | Domain/Family name |
---|---|
InterPro | Ig-like_fold |
InterPro | Ig_E-set |
InterPro | IPT_dom |
InterPro | Plexin |
InterPro | Plexin_cytoplasmic_RasGAP_dom |
InterPro | Plexin_repeat |
InterPro | PSI |
InterPro | Rho_GTPase_activation_prot |
InterPro | Semap_dom |
InterPro | Semap_dom_sf |
InterPro | TIG1_plexin |
InterPro | WD40/YVTN_repeat-like_dom_sf |
Pfam | Plexin_cytopl |
Pfam | PSI |
Pfam | Sema |
Pfam | TIG |
Pfam | TIG_plexin |