Frequently Asked Questions

1. Is registration necessary in PolarProtDb for data accession?

A: No. All data can be accessed freely without an account. Registration is only required to annotate new entries experiments.

2. How can I log in to the database?

A: In the upper right menu, You shall find an option to Log in, or to Register if you have not created an account before.

3. I have forgotten my password! How could I retrieve it?

A: Don't worry, you can always reset your credentials through an automated e-mail.

4. How can I annotate my experiments in PolarProtDb?

A: If you are logged in to the database, select the Add experiments option in the Annotate drop-down list in the upper right corner of the page. To submit your data, click on the Add new experiment button and fill all the text boxes or choose the proper options from the lists in the pop-up window. Please, be careful to enter valid UniProt ID or AC as sequence identifier, otherwise your data would not be submitted for inspection. Until the acceptance, your last annotations will remain to be displayed with red background in the list of your experiments.  

5. Can I modify or cancel my last submitted experiment?

A: If you are intended to change some information in your experiment after submitting, please, click on the edit button with blue filling on the right of the corresponding line in the table of your experiments. Otherwise, if you want to completely withdraw the added data, please, click on delete in the same row.

6. How can I leave a message for the administrators in relation with my uploaded experimental data?

A: If you submitted an experiment, you can find a three buttons on the right of the corresponding line in your annotation list. By clicking on one of them, you can modify, or cancel your submission, or contact with the administrators.

7. I have uploaded quite a few experiments yesterday, and none of them show up in the database

A: Checking the validity of the uploaded articles and experiments takes time. Do not worry if they have not been completed yet. In case there is a problem with the data or the format,  an administrator might contact you for the more precise details.

8. Can I suggest new features for the database?

A: You are welcome to do so. Please write a letter to the administrators, explaining exactly what you would like to see. Chances are, these features will be implemented in the next version!

9. How can I access the entry of a certain protein in PolarProtDb?

A: There are four different ways to reach the desired entry.

First, You can directly access it from the Browse menu (this solution may need to load in further entries of the database by simply scrolling down to the bottom of the page).

Select the UniProtKB ID of the given protein in the Protein filter of the Browse menu and click on the resulted entry!

Type the UniProtKB ID or UniProtKB AC of the sought protein in the search bar and click on the resulted entry!

You can use PolarProt API to reach the requested data under the following URL:[UniProtKB ID]

10. How can I cite PolarProtDb?

A: András Zeke, László Dobson, Levente István Szekeres, Tamás Langó and Gábor E. Tusnády (2020) PolarProtDb: a database of transmembrane and secreted proteins showing apical-basal polarity. Journal of Molecular Biology, 2020 Nov 10;166705.[PDF] [PubMed] [DOI].

11. What is PolarProtDb?

A: PolarProtDb is the most comprehensive database containing experimentally verified mammalian proteins that display polarized sorting or secretion, focusing at epithelial polarity. In addition to the source cells or tissues, homology-based inferences and transmembrane topology (if applicable) are all provided together. PolarProtDb also includes a detailed interface displaying information that may be relevant for trafficking, including post translational modifications (glycosylations, phosphorylations, etc), established conserved short linear motifs across orthologs and potential interaction partners.

12. What is evidence level?

A: In the  present database, the evidence level refers to the experimental method that evidenced the polarization feature of a particular protein expressed in a certain tissue

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