Gene name
Plxnb2 (KIAA0315)
Experiment(s)
For this entry:
F1P9S5_CANLF (Plxnb2)
| Species | Canis lupus familiaris |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Tan B,Yatim SMJM,Peng S,Gunaratne J,Hunziker W,Ludwig A (2020) The Mammalian Crumbs Complex Defines a Distinct Polarity Domain Apical of Epithelial Tight Junctions., Curr Biol, 30, 2791-2804.e6. [PubMed] [DOI] |
| Evidence level | Large-scale proteomics |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 19 | Signal peptide |
| 20 | 1271 | Extracellular |
| 1272 | 1292 | Membrane |
| 1293 | 1911 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Ig-like_fold |
| InterPro | Ig_E-set |
| InterPro | IPT_dom |
| InterPro | Plexin |
| InterPro | Plexin_cytoplasmic_RasGAP_dom |
| InterPro | Plexin_repeat |
| InterPro | PSI |
| InterPro | Rho_GTPase_activation_prot |
| InterPro | Semap_dom |
| InterPro | Semap_dom_sf |
| InterPro | TIG1_plexin |
| InterPro | WD40/YVTN_repeat-like_dom_sf |
| Pfam | Plexin_cytopl |
| Pfam | PSI |
| Pfam | Sema |
| Pfam | TIG |
| Pfam | TIG_plexin |