Gene name
Abcc1 (Mrp,Mrp1,Abcc1a,Abcc1b,Mdrap)
Experiment(s)
For this entry:
F6WW02_MACMU (Abcc1)
| Species | Macaca mulatta |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Klein DM,Wright SH,Cherrington NJ (2014) Localization of multidrug resistance-associated proteins along the blood-testis barrier in rat, macaque, and human testis., Drug Metab Dispos, 42, 89-93. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Testis |
| Cell | Sertoli cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 35 | Extracellular |
| 36 | 56 | Membrane |
| 57 | 74 | Cytoplasmic |
| 75 | 93 | Membrane |
| 94 | 103 | Extracellular |
| 104 | 124 | Membrane |
| 125 | 135 | Cytoplasmic |
| 136 | 157 | Membrane |
| 158 | 172 | Extracellular |
| 173 | 191 | Membrane |
| 192 | 320 | Cytoplasmic |
| 321 | 342 | Membrane |
| 343 | 363 | Extracellular |
| 364 | 385 | Membrane |
| 386 | 437 | Cytoplasmic |
| 438 | 459 | Membrane |
| 460 | 463 | Extracellular |
| 464 | 484 | Membrane |
| 485 | 547 | Cytoplasmic |
| 548 | 569 | Membrane |
| 570 | 581 | Extracellular |
| 582 | 603 | Membrane |
| 604 | 968 | Cytoplasmic |
| 969 | 990 | Membrane |
| 991 | 1016 | Extracellular |
| 1017 | 1038 | Membrane |
| 1039 | 1090 | Cytoplasmic |
| 1091 | 1111 | Membrane |
| 1112 | 1113 | Extracellular |
| 1114 | 1134 | Membrane |
| 1135 | 1197 | Cytoplasmic |
| 1198 | 1219 | Membrane |
| 1220 | 1226 | Extracellular |
| 1227 | 1248 | Membrane |
| 1249 | 1531 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | AAA+_ATPase |
| InterPro | ABC1_TM_dom |
| InterPro | ABC1_TM_sf |
| InterPro | ABC_transporter-like |
| InterPro | ABC_transporter_CS |
| InterPro | Multidrug-R_assoc |
| InterPro | P-loop_NTPase |
| Pfam | ABC_membrane |
| Pfam | ABC_tran |