Gene name
ATP1A1
Experiment(s)
For this entry:
AT1A1_RAT (ATP1A1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Arakaki X,McCleary P,Techy M,Chiang J,Kuo L,Fonteh AN,Armstrong B,Levy D,Harrington MG (2013) Na,K-ATPase alpha isoforms at the blood-cerebrospinal fluid-trigeminal nerve and blood-retina interfaces in the rat., Fluids Barriers CNS, 10, 14. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Choroid plexus |
| Cell | Ependymal cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 98 | Cytoplasmic |
| 99 | 116 | Membrane |
| 117 | 128 | Extracellular |
| 129 | 146 | Membrane |
| 147 | 294 | Cytoplasmic |
| 295 | 312 | Membrane |
| 313 | 320 | Extracellular |
| 321 | 339 | Membrane |
| 340 | 776 | Cytoplasmic |
| 777 | 795 | Membrane |
| 796 | 801 | Extracellular |
| 802 | 820 | Membrane |
| 821 | 850 | Cytoplasmic |
| 851 | 868 | Membrane |
| 869 | 919 | Extracellular |
| 920 | 937 | Membrane |
| 938 | 953 | Cytoplasmic |
| 954 | 971 | Membrane |
| 972 | 987 | Extracellular |
| 988 | 1005 | Membrane |
| 1006 | 1023 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | ATPase_P-typ_cation-transptr_C |
| InterPro | ATPase_P-typ_cation-transptr_N |
| InterPro | ATPase_P-typ_cyto_dom_N |
| InterPro | ATPase_P-typ_P_site |
| InterPro | ATPase_P-typ_TM_dom_sf |
| InterPro | ATPase_P-typ_transduc_dom_A_sf |
| InterPro | HAD-like_sf |
| InterPro | HAD_sf |
| InterPro | P-type_ATPase_IIC |
| InterPro | P_typ_ATPase |
| Pfam | Cation_ATPase_C |
| Pfam | Cation_ATPase_N |