Gene name
ATP1A1
Experiment(s)
For this entry:
AT1A1_MOUSE (ATP1A1)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Sato T,Mushiake S,Kato Y,Sato K,Sato M,Takeda N,Ozono K,Miki K,Kubo Y,Tsuji A,Harada R,Harada A (2007) The Rab8 GTPase regulates apical protein localization in intestinal cells., Nature, 448, 366-9. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 98 | Cytoplasmic |
| 99 | 116 | Membrane |
| 117 | 128 | Extracellular |
| 129 | 146 | Membrane |
| 147 | 294 | Cytoplasmic |
| 295 | 312 | Membrane |
| 313 | 320 | Extracellular |
| 321 | 339 | Membrane |
| 340 | 776 | Cytoplasmic |
| 777 | 795 | Membrane |
| 796 | 801 | Extracellular |
| 802 | 820 | Membrane |
| 821 | 850 | Cytoplasmic |
| 851 | 868 | Membrane |
| 869 | 919 | Extracellular |
| 920 | 937 | Membrane |
| 938 | 953 | Cytoplasmic |
| 954 | 971 | Membrane |
| 972 | 987 | Extracellular |
| 988 | 1005 | Membrane |
| 1006 | 1023 | Cytoplasmic |
Phosphorylation
| Position | Resource |
|---|---|
| 10 | 452054 |
| 16 | 449086 |
| 40 | 15719122 |
| 47 | 455248 |
| 55 | 461949 |
| 57 | 4765863 |
| 60 | 25283768 |
| 81 | 15719134 |
| 86 | 15719131 |
| 207 | 15719119 |
| 217 | 486205 |
| 219 | 486206 |
| 222 | 3143910 |
| 226 | 3147483 |
| 228 | 486108 |
| 260 | 454981 |
| 261 | 15402303 |
| 265 | 23084866 |
| 275 | 455241 |
| 369 | 2025077 |
| 370 | 2025081 |
| 375 | 2025093 |
| 378 | 2025097 |
| 380 | 1868296096 |
| 382 | 3989824 |
| 452 | 485853 |
| 454 | 15719125 |
| 484 | 10273345 |
| 485 | 4765875 |
| 499 | 27721247 |
| 542 | 458467 |
| 617 | 25731172 |
| 623 | 27723202 |
| 635 | 15719128 |
| 640 | 2049793 |
| 668 | 4765881 |
| 675 | 4765887 |
| 684 | 2150929 |
| 722 | 4765893 |
| 943 | 451649 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | ATPase_P-typ_cation-transptr_C |
| InterPro | ATPase_P-typ_cation-transptr_N |
| InterPro | ATPase_P-typ_cyto_dom_N |
| InterPro | ATPase_P-typ_P_site |
| InterPro | ATPase_P-typ_TM_dom_sf |
| InterPro | ATPase_P-typ_transduc_dom_A_sf |
| InterPro | HAD-like_sf |
| InterPro | HAD_sf |
| InterPro | P-type_ATPase_IIC |
| InterPro | P_typ_ATPase |
| Pfam | Cation_ATPase_C |
| Pfam | Cation_ATPase_N |
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| AT1B1_MOUSE | 2 | 24952909 , 17205597 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.