Gene name
SLC22A6 (Oat1,PAHT,Nkt)
Experiment(s)
For this entry:
S22A6_MOUSE (SLC22A6)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Breljak D,Brzica H,Sweet DH,Anzai N,Sabolic I (2013) Sex-dependent expression of Oat3 (Slc22a8) and Oat1 (Slc22a6) proteins in murine kidneys., Am J Physiol Renal Physiol, 304, F1114-26. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 14 | Cytoplasmic |
| 15 | 34 | Membrane |
| 35 | 129 | Extracellular |
| 130 | 149 | Membrane |
| 150 | 156 | Cytoplasmic |
| 157 | 177 | Membrane |
| 178 | 183 | Extracellular |
| 184 | 204 | Membrane |
| 205 | 214 | Cytoplasmic |
| 215 | 235 | Membrane |
| 236 | 242 | Extracellular |
| 243 | 262 | Membrane |
| 263 | 331 | Cytoplasmic |
| 332 | 351 | Membrane |
| 352 | 361 | Extracellular |
| 362 | 383 | Membrane |
| 384 | 390 | Cytoplasmic |
| 391 | 410 | Membrane |
| 411 | 418 | Extracellular |
| 419 | 439 | Membrane |
| 440 | 449 | Cytoplasmic |
| 450 | 470 | Membrane |
| 471 | 477 | Extracellular |
| 478 | 498 | Membrane |
| 499 | 545 | Cytoplasmic |
Phosphorylation
| Position | Resource |
|---|---|
| 249 | 25747695 |
Glycosylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | MFS_dom |
| InterPro | MFS_sugar_transport-like |
| InterPro | MFS_trans_sf |
| InterPro | Orgcat_transp/SVOP |
| Pfam | Sugar_tr |