Gene name
MGAM (MGA,MGAML)
Experiment(s)
For this entry:
MGA_HUMAN (MGAM)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Naim HY,Sterchi EE,Lentze MJ (1988) Structure, biosynthesis, and glycosylation of human small intestinal maltase-glucoamylase., J Biol Chem, 263, 19709-17. [PubMed] |
| Evidence level | Membrane preparation |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 13 | Cytoplasmic |
| 14 | 34 | Membrane |
| 35 | 1857 | Extracellular |
Phosphorylation
Glycosylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Gal_mutarotase_N |
| InterPro | Gal_mutarotase_sf_dom |
| InterPro | Glyco_hydro_31 |
| InterPro | Glyco_hydro_31_AS |
| InterPro | Glyco_hydro_31_CS |
| InterPro | Glyco_hydro_b |
| InterPro | Glycoside_hydrolase_SF |
| InterPro | P_trefoil_CS |
| InterPro | P_trefoil_dom |
| Pfam | Glyco_hydro_31 |
| Pfam | NtCtMGAM_N |
| Pfam | Trefoil |
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| GPR42_HUMAN | 3 | 32296183 |
| TM14B_HUMAN | 3 | 32296183 |
| CPLX4_HUMAN | 3 | 32296183 |
| VMAT1_HUMAN | 3 | 32296183 |
| AQP6_HUMAN | 3 | 32296183 |
| CR3L1_HUMAN | 3 | 32296183 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.