Gene name

MGAM (MGA,MGAML)

Experiment(s)

For this entry:
MGA_HUMAN (MGAM)
Species Homo sapiens
Localization Apical plasma membrane
Reference Naim HY,Sterchi EE,Lentze MJ (1988) Structure, biosynthesis, and glycosylation of human small intestinal maltase-glucoamylase., J Biol Chem, 263, 19709-17.
[PubMed]
Evidence level Membrane preparation
Organ Small intestine
Cell Enterocytes
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 13 Cytoplasmic
14 34 Membrane
35 1857 Extracellular
Phosphorylation
Glycosylation

Family and domain data

Database Domain/Family name
InterPro Gal_mutarotase_N
InterPro Gal_mutarotase_sf_dom
InterPro Glyco_hydro_31
InterPro Glyco_hydro_31_AS
InterPro Glyco_hydro_31_CS
InterPro Glyco_hydro_b
InterPro Glycoside_hydrolase_SF
InterPro P_trefoil_CS
InterPro P_trefoil_dom
Pfam Glyco_hydro_31
Pfam NtCtMGAM_N
Pfam Trefoil

Interactions

With (links to EBI) #Exp PubMed links
GPR42_HUMAN 3 32296183
TM14B_HUMAN 3 32296183
CPLX4_HUMAN 3 32296183
VMAT1_HUMAN 3 32296183
AQP6_HUMAN 3 32296183
CR3L1_HUMAN 3 32296183
Protein can be found in apical membrane, Protein can be found in basal membrane, Protein can be found both membranes, Localisation is unknown.

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