Gene name
Slc2a1 (Glut1)
Experiment(s)
For this entry:
GTR1_RAT (Slc2a1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Linden KC,DeHaan CL,Zhang Y,Glowacka S,Cox AJ,Kelly DJ,Rogers S (2006) Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy., Am J Physiol Renal Physiol, 290, F205-13. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
GTR1_RAT (Slc2a1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Macheda ML,Williams ED,Best JD,Wlodek ME,Rogers S (2003) Expression and localisation of GLUT1 and GLUT12 glucose transporters in the pregnant and lactating rat mammary gland., Cell Tissue Res, 311, 91-7. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Mammary gland |
| Cell | Acinar cells |
| Notes |
GTR1_RAT (Slc2a1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Non polar membrane |
| Reference |
Sugasawa K,Deguchi J,Okami T,Yamamoto A,Omori K,Uyama M,Tashiro Y (1994) Immunocytochemical analyses of distributions of Na, K-ATPase and GLUT1, insulin and transferrin receptors in the developing retinal pigment epithelial cells., Cell Struct Funct, 19, 21-8. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Retina |
| Cell | Pigment epithel cells |
| Notes |
GTR1_RAT (Slc2a1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Non polar membrane |
| Reference |
Roberts LM,Black DS,Raman C,Woodford K,Zhou M,Haggerty JE,Yan AT,Cwirla SE,Grindstaff KK (2008) Subcellular localization of transporters along the rat blood-brain barrier and blood-cerebral-spinal fluid barrier by in vivo biotinylation., Neuroscience, 155, 423-38. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Vessels |
| Cell | Brain capillary endothelial cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 14 | Cytoplasmic |
| 15 | 35 | Membrane |
| 36 | 65 | Extracellular |
| 66 | 86 | Membrane |
| 87 | 93 | Cytoplasmic |
| 94 | 113 | Membrane |
| 114 | 120 | Extracellular |
| 121 | 141 | Membrane |
| 142 | 155 | Cytoplasmic |
| 156 | 175 | Membrane |
| 176 | 187 | Extracellular |
| 188 | 207 | Membrane |
| 208 | 272 | Cytoplasmic |
| 273 | 292 | Membrane |
| 293 | 308 | Extracellular |
| 309 | 328 | Membrane |
| 329 | 335 | Cytoplasmic |
| 336 | 354 | Membrane |
| 355 | 367 | Extracellular |
| 368 | 389 | Membrane |
| 390 | 404 | Cytoplasmic |
| 405 | 426 | Membrane |
| 427 | 432 | Extracellular |
| 433 | 452 | Membrane |
| 453 | 492 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Glu_transpt_1 |
| InterPro | MFS_dom |
| InterPro | MFS_sugar_transport-like |
| InterPro | MFS_trans_sf |
| InterPro | Sugar/inositol_transpt |
| InterPro | Sugar_transporter_CS |
| Pfam | Sugar_tr |