Gene name
Slc2a1 (Glut1)
Experiment(s)
For this entry:
GTR1_RABIT (Slc2a1)
| Species | Oryctolagus cuniculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Inukai K,Takata K,Asano T,Katagiri H,Ishihara H,Nakazaki M,Fukushima Y,Yazaki Y,Kikuchi M,Oka Y (1997) Targeting of GLUT1-GLUT5 chimeric proteins in the polarized cell line Caco-2., Mol Endocrinol, 11, 442-9. [PubMed] [DOI] |
| Evidence level | Antibody staining + sub-protein manipulation |
| Organ | Large intestine |
| Cell | CACO-2 cells (enterocytes) |
| Notes | The large intracellular loop was identified as a determinat of sorting |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 14 | Cytoplasmic |
| 15 | 35 | Membrane |
| 36 | 65 | Extracellular |
| 66 | 86 | Membrane |
| 87 | 93 | Cytoplasmic |
| 94 | 113 | Membrane |
| 114 | 120 | Extracellular |
| 121 | 141 | Membrane |
| 142 | 155 | Cytoplasmic |
| 156 | 174 | Membrane |
| 175 | 187 | Extracellular |
| 188 | 207 | Membrane |
| 208 | 272 | Cytoplasmic |
| 273 | 292 | Membrane |
| 293 | 308 | Extracellular |
| 309 | 328 | Membrane |
| 329 | 335 | Cytoplasmic |
| 336 | 354 | Membrane |
| 355 | 367 | Extracellular |
| 368 | 389 | Membrane |
| 390 | 404 | Cytoplasmic |
| 405 | 426 | Membrane |
| 427 | 432 | Extracellular |
| 433 | 452 | Membrane |
| 453 | 492 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Glu_transpt_1 |
| InterPro | MFS_dom |
| InterPro | MFS_sugar_transport-like |
| InterPro | MFS_trans_sf |
| InterPro | Sugar/inositol_transpt |
| InterPro | Sugar_transporter_CS |
| Pfam | Sugar_tr |