PolarProtDb

Gene name

DPP4 (CD26,ADCP2)

Experiment(s)

For this entry:

DPP4_RAT (DPP4)

Species	Rattus norvegicus
Localization	Apical plasma membrane
Reference	Casanova JE,Mishumi Y,Ikehara Y,Hubbard AL,Mostov KE (1991) Direct apical sorting of rat liver dipeptidylpeptidase IV expressed in Madin-Darby canine kidney cells., J Biol Chem, 266, 24428-32. [PubMed]
Evidence level	Antibody staining
Organ	Kidney
Cell	MDCK cells (distal tubule)
Notes

For ortholog entries:

DPP4_MOUSE

DPP4_HUMAN

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).

CCTOP topology prediction

Start	End	Localisation
1	6	Cytoplasmic
7	26	Membrane
27	767	Extracellular

Glycosylation

Position	Site resource	PubMed link(s)
83	UniProtKB	16768443
83	dbPTM	16768443
83	PDB	16768443
83	PDB	29765112
90	UniProtKB	16768443
90	dbPTM	16768443
90	PDB	29765112
90	PDB	16768443
148	UniProtKB
217	PDB	29765112
217	UniProtKB
227	UniProtKB	16768443
227	dbPTM	16768443
227	PDB	16768443
227	PDB	29765112
319	UniProtKB	16768443
319	dbPTM	16768443
319	PDB	29765112
319	PDB	16768443
521	PDB	16768443
521	PDB	29765112
521	dbPTM	16768443
521	UniProtKB	16768443
686	UniProtKB

Family and domain data

Database	Domain/Family name
InterPro	AB_hydrolase
InterPro	DPPIV_rep
InterPro	Pept_S9_AS
InterPro	Peptidase_S9
InterPro	Peptidase_S9B_N
InterPro	Peptidase_S9B_N_sf
Pfam	DPPIV_N
Pfam	DPPIV_rep
Pfam	Peptidase_S9