Gene name
DPP4 (CD26,ADCP2)
Experiment(s)
For this entry:
DPP4_MOUSE (DPP4)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Sato T,Mushiake S,Kato Y,Sato K,Sato M,Takeda N,Ozono K,Miki K,Kubo Y,Tsuji A,Harada R,Harada A (2007) The Rab8 GTPase regulates apical protein localization in intestinal cells., Nature, 448, 366-9. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes | Apical localization dependent on Rab8 |
DPP4_MOUSE (DPP4)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Rius M,Nies AT,Hummel-Eisenbeiss J,Jedlitschky G,Keppler D (2003) Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane., Hepatology, 38, 374-84. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Liver |
| Cell | Hepatocytes |
| Notes |
DPP4_MOUSE (DPP4)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Rius M,Nies AT,Hummel-Eisenbeiss J,Jedlitschky G,Keppler D (2003) Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane., Hepatology, 38, 374-84. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Liver |
| Cell | HEPG2 cells (hepatocytes) |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 6 | Cytoplasmic |
| 7 | 26 | Membrane |
| 27 | 760 | Extracellular |
Phosphorylation
Glycosylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | AB_hydrolase |
| InterPro | DPPIV_rep |
| InterPro | Pept_S9_AS |
| InterPro | Peptidase_S9 |
| InterPro | Peptidase_S9B_N |
| InterPro | Peptidase_S9B_N_sf |
| Pfam | DPPIV_N |
| Pfam | DPPIV_rep |
| Pfam | Peptidase_S9 |