Gene name
CRB1 (Crb1_predicted)
Experiment(s)
For this entry:
CRUM1_MOUSE (CRB1)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
van de Pavert SA,Kantardzhieva A,Malysheva A,Meuleman J,Versteeg I,Levelt C,Klooster J,Geiger S,Seeliger MW,Rashbass P,Le Bivic A,Wijnholds J (2004) Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure., J Cell Sci, 117, 4169-77. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Retina |
| Cell | Photoreceptor cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 28 | Signal peptide |
| 29 | 1345 | Extracellular |
| 1346 | 1367 | Membrane |
| 1368 | 1405 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | ConA-like_dom_sf |
| InterPro | EGF-like_Ca-bd_dom |
| InterPro | EGF-like_CS |
| InterPro | EGF-like_dom |
| InterPro | EGF-type_Asp/Asn_hydroxyl_site |
| InterPro | EGF_Ca-bd_CS |
| InterPro | Growth_fac_rcpt_cys_sf |
| InterPro | Laminin_G |
| Pfam | EGF |
| Pfam | hEGF |
| Pfam | Laminin_G_2 |