PolarProtDb

Gene name

Ca4

Experiment(s)

For this entry:

CAH4_RAT (Ca4)

Species	Rattus norvegicus
Localization	Apical plasma membrane
Reference	Brown D,Zhu XL,Sly WS (1990) Localization of membrane-associated carbonic anhydrase type IV in kidney epithelial cells., Proc Natl Acad Sci U S A, 87, 7457-61. [PubMed] [DOI]
Evidence level	Antibody staining
Organ	Kidney
Cell	Proximal tubules
Notes

For ortholog entries:

CAH4_BOVIN

CAH4_HUMAN

CAH4_RABIT

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).

CCTOP topology prediction

Start	End	Localisation
1	20	Signal peptide
21	286	Extracellular
287	308	Membrane
309	309	Cytoplasmic

Glycosylation

Position	Site resource	Glycan resource	PubMed link(s)
193	UniCarbKB	$WURCS=2.0/3,8,7/[uxxxxm][uxxxxh_2*NCC/3=O][uxxxxh]/1-2-2-2-2-3-3-3/a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?$	24090084
193	UniCarbKB		24090084
193	UniCarbKB		24090084
193	UniCarbKB	$WURCS=2.0/3,9,8/[uxxxxm][uxxxxh_2*NCC/3=O][uxxxxh]/1-2-2-2-2-2-3-3-3/a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?$	24090084
193	dbPTM		24090084
193	UniProtKB		24090084

Family and domain data

Database	Domain/Family name
InterPro	CA4/CA15
InterPro	CA_dom
InterPro	CA_dom_sf
InterPro	Carbonic_anhydrase_a-class
InterPro	Carbonic_anhydrase_a-class_CS
InterPro	Carbonic_anhydrase_CA4
Pfam	Carb_anhydrase