Gene name
Ca4
Experiment(s)
For this entry:
CAH4_BOVIN (Ca4)
| Species | Bos taurus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Sun XC,Li J,Cui M,Bonanno JA (2008) Role of carbonic anhydrase IV in corneal endothelial HCO3- transport., Invest Ophthalmol Vis Sci, 49, 1048-55. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Cornea |
| Cell | Epithelial cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 20 | Signal peptide |
| 21 | 288 | Extracellular |
| 289 | 311 | Membrane |
| 312 | 312 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | CA4/CA15 |
| InterPro | CA_dom |
| InterPro | CA_dom_sf |
| InterPro | Carbonic_anhydrase_a-class |
| InterPro | Carbonic_anhydrase_CA4 |
| Pfam | Carb_anhydrase |