Gene name
AQP3
Experiment(s)
For this entry:
AQP3_RAT (AQP3)
| Species | Rattus norvegicus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Ishibashi K,Sasaki S,Fushimi K,Uchida S,Kuwahara M,Saito H,Furukawa T,Nakajima K,Yamaguchi Y,Gojobori T (1994) Molecular cloning and expression of a member of the aquaporin family with permeability to glycerol and urea in addition to water expressed at the basolateral membrane of kidney collecting duct cells., Proc Natl Acad Sci U S A, 91, 6269-73. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Collecting ducts |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 24 | Cytoplasmic |
| 25 | 42 | Membrane |
| 43 | 57 | Extracellular |
| 58 | 75 | Membrane |
| 76 | 78 | Cytoplasmic |
| 79 | 92 | Re-entrant loop |
| 93 | 101 | Cytoplasmic |
| 102 | 119 | Membrane |
| 120 | 160 | Extracellular |
| 161 | 178 | Membrane |
| 179 | 189 | Cytoplasmic |
| 190 | 207 | Membrane |
| 208 | 210 | Extracellular |
| 211 | 227 | Re-entrant loop |
| 228 | 243 | Extracellular |
| 244 | 261 | Membrane |
| 262 | 292 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Aquaporin-like |
| InterPro | Aquaporin_3 |
| InterPro | MIP |
| InterPro | MIP_CS |
| Pfam | MIP |