Gene name
AQP3
Experiment(s)
For this entry:
AQP3_MOUSE (AQP3)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Yu W,Hill WG,Apodaca G,Zeidel ML (2011) Expression and distribution of transient receptor potential (TRP) channels in bladder epithelium., Am J Physiol Renal Physiol, 300, F49-59. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Bladder |
| Cell | Urothelial cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 24 | Cytoplasmic |
| 25 | 42 | Membrane |
| 43 | 57 | Extracellular |
| 58 | 75 | Membrane |
| 76 | 78 | Cytoplasmic |
| 79 | 93 | Re-entrant loop |
| 94 | 100 | Cytoplasmic |
| 101 | 119 | Membrane |
| 120 | 159 | Extracellular |
| 160 | 178 | Membrane |
| 179 | 189 | Cytoplasmic |
| 190 | 207 | Membrane |
| 208 | 211 | Extracellular |
| 212 | 226 | Re-entrant loop |
| 227 | 242 | Extracellular |
| 243 | 261 | Membrane |
| 262 | 292 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Aquaporin-like |
| InterPro | Aquaporin_3 |
| InterPro | MIP |
| InterPro | MIP_CS |
| Pfam | MIP |