Gene name
AQP3
Experiment(s)
For this entry:
AQP3_HUMAN (AQP3)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Mobasheri A,Shakibaei M,Marples D (2004) Immunohistochemical localization of aquaporin 10 in the apical membranes of the human ileum: a potential pathway for luminal water and small solute absorption., Histochem Cell Biol, 121, 463-71. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes |
AQP3_HUMAN (AQP3)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Mobasheri A,Shakibaei M,Marples D (2004) Immunohistochemical localization of aquaporin 10 in the apical membranes of the human ileum: a potential pathway for luminal water and small solute absorption., Histochem Cell Biol, 121, 463-71. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Goblet cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 24 | Cytoplasmic |
| 25 | 42 | Membrane |
| 43 | 57 | Extracellular |
| 58 | 75 | Membrane |
| 76 | 78 | Cytoplasmic |
| 79 | 92 | Re-entrant loop |
| 93 | 101 | Cytoplasmic |
| 102 | 119 | Membrane |
| 120 | 160 | Extracellular |
| 161 | 178 | Membrane |
| 179 | 189 | Cytoplasmic |
| 190 | 207 | Membrane |
| 208 | 210 | Extracellular |
| 211 | 229 | Re-entrant loop |
| 230 | 243 | Extracellular |
| 244 | 261 | Membrane |
| 262 | 292 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Aquaporin-like |
| InterPro | Aquaporin_3 |
| InterPro | MIP |
| InterPro | MIP_CS |
| Pfam | MIP |
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| MGST3_HUMAN | 3 | 32296183 |
| SSMM1_HUMAN | 3 | 32296183 |
| TM107_HUMAN | 3 | 32296183 |
| LEUTX_HUMAN | 3 | 32296183 |
| NRAC_HUMAN | 3 | 32296183 |
| STX1A_HUMAN | 3 | 32296183 |
| MRM1_HUMAN | 3 | 32296183 |
| TNFA_HUMAN | 3 | 32296183 |
| AQP3_HUMAN | 3 | 32296183 |
| 3HIDH_HUMAN | 3 | 32296183 |
| TMM42_HUMAN | 3 | 32296183 |
| PLP2_HUMAN | 3 | 32296183 |
| TM86A_HUMAN | 3 | 32296183 |
| SGPL1_HUMAN | 3 | 32296183 |
| GPX8_HUMAN | 3 | 32296183 |
| OLFM4_HUMAN | 3 | 32296183 |
| EVI2B_HUMAN | 3 | 32296183 |
| GP152_HUMAN | 3 | 32296183 |
| VASN_HUMAN | 3 | 32296183 |
| SAR1A_HUMAN | 3 | 32296183 |
| CD79A_HUMAN | 3 | 32296183 |
| MFF_HUMAN | 3 | 32296183 |
| MUC1_HUMAN | 3 | 32296183 |
| GIMA5_HUMAN | 3 | 32296183 |
| F209A_HUMAN | 3 | 32296183 |
| ERGI3_HUMAN | 3 | 32296183 |
| ERG28_HUMAN | 3 | 32296183 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.