Gene name
AGRN (AGRIN)
Experiment(s)
For this entry:
AGRIN_HUMAN (AGRN)
Species | Homo sapiens |
---|---|
Localization | Non polar membrane |
Reference |
Touzelet O,Broadbent L,Armstrong SD,Aljabr W,Cloutman-Green E,Power UF,Hiscox JA (2020) The Secretome Profiling of a Pediatric Airway Epithelium Infected with hRSV Identified Aberrant Apical/Basolateral Trafficking and Novel Immune Modulating (CXCL6, CXCL16, CSF3) and Antiviral (CEACAM1) Proteins., Mol Cell Proteomics, 19, 793-807. [PubMed] [DOI] |
Evidence level | Large-scale proteomics |
Organ | Lung |
Cell | Airway epithel cells |
Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start | End | Localisation |
---|---|---|
1 | 2068 | Extracellular |
Phosphorylation
Glycosylation
Family and domain data
Database | Domain/Family name |
---|---|
InterPro | ConA-like_dom_sf |
InterPro | EGF-like_Ca-bd_dom |
InterPro | EGF-like_dom |
InterPro | FacI_MAC |
InterPro | Fol_N |
InterPro | Kazal_dom |
InterPro | Kazal_dom_sf |
InterPro | Laminin_EGF |
InterPro | Laminin_G |
InterPro | NtA_dom |
InterPro | SEA_dom |
InterPro | SEA_dom_sf |
InterPro | TIMP-like_OB-fold |
Pfam | EGF |
Pfam | Kazal_1 |
Pfam | Kazal_2 |
Pfam | Laminin_EGF |
Pfam | Laminin_G_1 |
Pfam | NtA |
Pfam | SEA |
Interactions
With (links to EBI) | #Exp | PubMed links |
---|---|---|
ATX7_HUMAN | 2 | 21078624 |
MERL_HUMAN | 2 | 28514442 |
ESR1_HUMAN | 2 | 31527615 |
A4_HUMAN | 3 | 10673326 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.