Gene name

ABCG2 (Abcp,BCRP,Bcrp1,MXR,BMDP)

Experiment(s)

For this entry:
ABCG2_MOUSE (ABCG2)
Species Mus musculus
Localization Apical plasma membrane
Reference Tomioka NH,Tamura Y,Takada T,Shibata S,Suzuki H,Uchida S,Hosoyamada M (2016) Immunohistochemical and in situ hybridization study of urate transporters GLUT9/URATv1, ABCG2, and URAT1 in the murine brain., Fluids Barriers CNS, 13, 22.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Vessels
Cell Brain capillary endothelial cells
Notes
ABCG2_MOUSE (ABCG2)
Species Mus musculus
Localization Apical plasma membrane
Reference Wang H,Wu X,Hudkins K,Mikheev A,Zhang H,Gupta A,Unadkat JD,Mao Q (2006) Expression of the breast cancer resistance protein (Bcrp1/Abcg2) in tissues from pregnant mice: effects of pregnancy and correlations with nuclear receptors., Am J Physiol Endocrinol Metab, 291, E1295-304.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Placenta
Cell Trophoblast cells
Notes
ABCG2_MOUSE (ABCG2)
Species Mus musculus
Localization Apical plasma membrane
Reference Wang H,Wu X,Hudkins K,Mikheev A,Zhang H,Gupta A,Unadkat JD,Mao Q (2006) Expression of the breast cancer resistance protein (Bcrp1/Abcg2) in tissues from pregnant mice: effects of pregnancy and correlations with nuclear receptors., Am J Physiol Endocrinol Metab, 291, E1295-304.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Kidney
Cell Proximal tubules
Notes
ABCG2_MOUSE (ABCG2)
Species Mus musculus
Localization Apical plasma membrane
Reference Wang H,Wu X,Hudkins K,Mikheev A,Zhang H,Gupta A,Unadkat JD,Mao Q (2006) Expression of the breast cancer resistance protein (Bcrp1/Abcg2) in tissues from pregnant mice: effects of pregnancy and correlations with nuclear receptors., Am J Physiol Endocrinol Metab, 291, E1295-304.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Small intestine
Cell Enterocytes
Notes
ABCG2_MOUSE (ABCG2)
Species Mus musculus
Localization Apical plasma membrane
Reference Wang H,Wu X,Hudkins K,Mikheev A,Zhang H,Gupta A,Unadkat JD,Mao Q (2006) Expression of the breast cancer resistance protein (Bcrp1/Abcg2) in tissues from pregnant mice: effects of pregnancy and correlations with nuclear receptors., Am J Physiol Endocrinol Metab, 291, E1295-304.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Liver
Cell Hepatocytes
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 392 Cytoplasmic
393 414 Membrane
415 427 Extracellular
428 449 Membrane
450 476 Cytoplasmic
477 498 Membrane
499 505 Extracellular
506 527 Membrane
528 534 Cytoplasmic
535 556 Membrane
557 630 Extracellular
631 652 Membrane
653 657 Cytoplasmic

Family and domain data

Database Domain/Family name
InterPro AAA+_ATPase
InterPro ABC_2_trans
InterPro ABC_transporter-like
InterPro ABCG2
InterPro P-loop_NTPase
Pfam ABC2_membrane
Pfam ABC_tran

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