Gene name
SLC22A4 (OCTN1,ETT,UT2H)
Experiment(s)
For this entry:
A0A5F9CMA4_RABIT (SLC22A4)
| Species | Oryctolagus cuniculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Garrett Q,Xu S,Simmons PA,Vehige J,Flanagan JL,Willcox MD (2008) Expression and localization of carnitine/organic cation transporter OCTN1 and OCTN2 in ocular epithelium., Invest Ophthalmol Vis Sci, 49, 4844-9. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Cornea |
| Cell | Epithelial cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 19 | Cytoplasmic |
| 20 | 39 | Membrane |
| 40 | 143 | Extracellular |
| 144 | 163 | Membrane |
| 164 | 170 | Cytoplasmic |
| 171 | 190 | Membrane |
| 191 | 196 | Extracellular |
| 197 | 218 | Membrane |
| 219 | 228 | Cytoplasmic |
| 229 | 250 | Membrane |
| 251 | 257 | Extracellular |
| 258 | 277 | Membrane |
| 278 | 342 | Cytoplasmic |
| 343 | 362 | Membrane |
| 363 | 371 | Extracellular |
| 372 | 393 | Membrane |
| 394 | 400 | Cytoplasmic |
| 401 | 420 | Membrane |
| 421 | 427 | Extracellular |
| 428 | 449 | Membrane |
| 450 | 460 | Cytoplasmic |
| 461 | 482 | Membrane |
| 483 | 488 | Extracellular |
| 489 | 509 | Membrane |
| 510 | 557 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | MFS_dom |
| InterPro | MFS_sugar_transport-like |
| InterPro | MFS_trans_sf |
| InterPro | Orgcat_transp/SVOP |
| InterPro | Sugar_transporter_CS |
| Pfam | Sugar_tr |