Gene name

NGFR (Tnfrsf16)

Experiment(s)

For this entry:
TNR16_RAT (NGFR)
Species Rattus norvegicus
Localization Apical plasma membrane
Reference Yeaman C,Le Gall AH,Baldwin AN,Monlauzeur L,Le Bivic A,Rodriguez-Boulan E (1997) The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cells., J Cell Biol, 139, 929-40.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Kidney
Cell MDCK cells (distal tubule)
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 29 Signal peptide
30 254 Extracellular
255 273 Membrane
274 425 Cytoplasmic
Phosphorylation
Position Resource
278 9993601
337 454435
Glycosylation
Position Site resource Glycan resource PubMed link(s)
61 UniProtKB 20036257

Family and domain data

Database Domain/Family name
InterPro DEATH-like_dom_sf
InterPro Death_domain
InterPro TNFR/NGFR_Cys_rich_reg
InterPro TNFR16_TM
InterPro TNFR_16
InterPro TNFRSF16_N
Pfam Death
Pfam TNFR_16_TM
Pfam TNFR_c6

Interactions

With (links to EBI) #Exp PubMed links
A4_HUMAN 2 11756426
Protein can be found in apical membrane, Protein can be found in basal membrane, Protein can be found both membranes, Localisation is unknown.

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