Gene name
TG
Experiment(s)
For this entry:
THYG_RAT (TG)
| Species | Rattus norvegicus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Martín-Belmonte F,Arvan P,Alonso MA (2001) MAL mediates apical transport of secretory proteins in polarized epithelial Madin-Darby canine kidney cells., J Biol Chem, 276, 49337-42. [PubMed] [DOI] |
| Evidence level | Selective medium analysis |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes | Secretion depended on MAL protein |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 2768 | Extracellular |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | AB_hydrolase |
| InterPro | CarbesteraseB |
| InterPro | Carboxylesterase_B_CS |
| InterPro | Thyroglobulin |
| InterPro | Thyroglobulin_1 |
| InterPro | Thyroglobulin_1_sf |
| InterPro | Tyr-kin_ephrin_A/B_rcpt-like |
| Pfam | COesterase |
| Pfam | Ephrin_rec_like |
| Pfam | Thyroglobulin_1 |