Gene name
SLC9A1 (NHE1,APNH1)
Experiment(s)
For this entry:
SL9A1_RAT (SLC9A1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Nejsum LN,Praetorius J,Nielsen S (2005) NKCC1 and NHE1 are abundantly expressed in the basolateral plasma membrane of secretory coil cells in rat, mouse, and human sweat glands., Am J Physiol Cell Physiol, 289, C333-40. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Sweat glands |
| Cell | Secretory cells |
| Notes |
SL9A1_RAT (SLC9A1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Nejsum LN,Praetorius J,Nielsen S (2005) NKCC1 and NHE1 are abundantly expressed in the basolateral plasma membrane of secretory coil cells in rat, mouse, and human sweat glands., Am J Physiol Cell Physiol, 289, C333-40. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Collecting ducts |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 15 | Cytoplasmic |
| 16 | 33 | Membrane |
| 34 | 107 | Extracellular |
| 108 | 126 | Membrane |
| 127 | 135 | Cytoplasmic |
| 136 | 153 | Membrane |
| 154 | 163 | Extracellular |
| 164 | 183 | Membrane |
| 184 | 192 | Cytoplasmic |
| 193 | 212 | Membrane |
| 213 | 228 | Extracellular |
| 229 | 249 | Membrane |
| 250 | 258 | Cytoplasmic |
| 259 | 277 | Membrane |
| 278 | 296 | Extracellular |
| 297 | 322 | Membrane |
| 323 | 331 | Cytoplasmic |
| 332 | 348 | Membrane |
| 349 | 350 | Extracellular |
| 351 | 371 | Membrane |
| 372 | 388 | Cytoplasmic |
| 389 | 407 | Membrane |
| 408 | 416 | Extracellular |
| 417 | 438 | Membrane |
| 439 | 454 | Cytoplasmic |
| 455 | 473 | Membrane |
| 474 | 482 | Extracellular |
| 483 | 503 | Membrane |
| 504 | 820 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Cation/H_exchanger |
| InterPro | Cation/H_exchanger_CPA1 |
| InterPro | Na/H_exchanger_1 |
| InterPro | NaH_exchanger |
| InterPro | NHE_CaM-bd |
| Pfam | Na_H_Exchanger |
| Pfam | NEXCaM_BD |