Gene name
Slc26a4 (Pds)
Experiment(s)
For this entry:
S26A4_MOUSE (Slc26a4)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Verlander JW,Hassell KA,Royaux IE,Glapion DM,Wang ME,Everett LA,Green ED,Wall SM (2003) Deoxycorticosterone upregulates PDS (Slc26a4) in mouse kidney: role of pendrin in mineralocorticoid-induced hypertension., Hypertension, 42, 356-62. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Inner ear |
| Cell | Cochlear duct cells |
| Notes |
S26A4_MOUSE (Slc26a4)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Verlander JW,Hassell KA,Royaux IE,Glapion DM,Wang ME,Everett LA,Green ED,Wall SM (2003) Deoxycorticosterone upregulates PDS (Slc26a4) in mouse kidney: role of pendrin in mineralocorticoid-induced hypertension., Hypertension, 42, 356-62. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Beta intercalated cells |
| Notes |
S26A4_MOUSE (Slc26a4)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Verlander JW,Miller RT,Frank AE,Royaux IE,Kim YH,Weiner ID (2003) Localization of the ammonium transporter proteins RhBG and RhCG in mouse kidney., Am J Physiol Renal Physiol, 284, F323-37. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Collecting ducts |
| Notes |
S26A4_MOUSE (Slc26a4)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Bronckers AL,Guo J,Zandieh-Doulabi B,Bervoets TJ,Lyaruu DM,Li X,Wangemann P,DenBesten P (2011) Developmental expression of solute carrier family 26A member 4 (SLC26A4/pendrin) during amelogenesis in developing rodent teeth., Eur J Oral Sci, 119 Suppl 1, 185-92. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Teeth |
| Cell | Ameloblasts |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 87 | Cytoplasmic |
| 88 | 108 | Membrane |
| 109 | 113 | Extracellular |
| 114 | 131 | Membrane |
| 132 | 135 | Cytoplasmic |
| 136 | 156 | Membrane |
| 157 | 185 | Extracellular |
| 186 | 213 | Membrane |
| 214 | 218 | Cytoplasmic |
| 219 | 239 | Membrane |
| 240 | 268 | Extracellular |
| 269 | 285 | Membrane |
| 286 | 299 | Cytoplasmic |
| 300 | 317 | Membrane |
| 318 | 347 | Extracellular |
| 348 | 368 | Membrane |
| 369 | 384 | Cytoplasmic |
| 385 | 406 | Membrane |
| 407 | 421 | Extracellular |
| 422 | 442 | Membrane |
| 443 | 447 | Cytoplasmic |
| 448 | 468 | Membrane |
| 469 | 482 | Extracellular |
| 483 | 510 | Membrane |
| 511 | 780 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Pendrin |
| InterPro | S04_transporter_CS |
| InterPro | SLC26A/SulP_dom |
| InterPro | SLC26A/SulP_fam |
| InterPro | STAS_dom |
| InterPro | STAS_dom_sf |
| Pfam | STAS |
| Pfam | Sulfate_transp |