Gene name
SLC23A2 (KIAA0238,SVCT2,YSPL2,NBTL1,SLC23A1)
Experiment(s)
For this entry:
S23A2_MOUSE (SLC23A2)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Ulloa V,Saldivia N,Ferrada L,Salazar K,Martínez F,Silva-Alvarez C,Magdalena R,Oviedo MJ,Montecinos H,Torres-Vergara P,Cifuentes M,Nualart F (2019) Basal Sodium-Dependent Vitamin C Transporter 2 polarization in choroid plexus explant cells in normal or scorbutic conditions., Sci Rep, 9, 14422. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Choroid plexus |
| Cell | Ependymal cells |
| Notes | Localization of transporter is labile: It can redistribute to vesicles |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 103 | Cytoplasmic |
| 104 | 124 | Membrane |
| 125 | 139 | Extracellular |
| 140 | 158 | Membrane |
| 159 | 163 | Cytoplasmic |
| 164 | 182 | Membrane |
| 183 | 212 | Extracellular |
| 213 | 233 | Membrane |
| 234 | 238 | Cytoplasmic |
| 239 | 257 | Membrane |
| 258 | 266 | Extracellular |
| 267 | 285 | Membrane |
| 286 | 308 | Cytoplasmic |
| 309 | 330 | Membrane |
| 331 | 369 | Extracellular |
| 370 | 390 | Membrane |
| 391 | 455 | Cytoplasmic |
| 456 | 476 | Membrane |
| 477 | 483 | Extracellular |
| 484 | 504 | Membrane |
| 505 | 513 | Cytoplasmic |
| 514 | 532 | Membrane |
| 533 | 547 | Extracellular |
| 548 | 566 | Membrane |
| 567 | 648 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | SlC23A2 |
| InterPro | Xan_ur_permease |
| InterPro | Xant/urac/vitC |
| Pfam | Xan_ur_permease |