Gene name
SLC15A1 (Pept1)
Experiment(s)
For this entry:
S15A1_MOUSE (SLC15A1)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Sato T,Mushiake S,Kato Y,Sato K,Sato M,Takeda N,Ozono K,Miki K,Kubo Y,Tsuji A,Harada R,Harada A (2007) The Rab8 GTPase regulates apical protein localization in intestinal cells., Nature, 448, 366-9. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes | Apical localization dependent on Rab8 |
S15A1_MOUSE (SLC15A1)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Groneberg DA,Döring F,Eynott PR,Fischer A,Daniel H (2001) Intestinal peptide transport: ex vivo uptake studies and localization of peptide carrier PEPT1., Am J Physiol Gastrointest Liver Physiol, 281, G697-704. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 13 | Cytoplasmic |
| 14 | 31 | Membrane |
| 32 | 53 | Extracellular |
| 54 | 73 | Membrane |
| 74 | 82 | Cytoplasmic |
| 83 | 103 | Membrane |
| 104 | 121 | Extracellular |
| 122 | 139 | Membrane |
| 140 | 164 | Cytoplasmic |
| 165 | 184 | Membrane |
| 185 | 200 | Extracellular |
| 201 | 218 | Membrane |
| 219 | 278 | Cytoplasmic |
| 279 | 297 | Membrane |
| 298 | 326 | Extracellular |
| 327 | 344 | Membrane |
| 345 | 360 | Cytoplasmic |
| 361 | 378 | Membrane |
| 379 | 588 | Extracellular |
| 589 | 604 | Membrane |
| 605 | 620 | Cytoplasmic |
| 621 | 640 | Membrane |
| 641 | 649 | Extracellular |
| 650 | 668 | Membrane |
| 669 | 709 | Cytoplasmic |
Glycosylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | MFS_trans_sf |
| InterPro | Oligopep_transport |
| InterPro | POT_fam |
| InterPro | PTR2_symporter_CS |
| Pfam | PTR2 |