Gene name
SLC15A1 (Pept1)
Experiment(s)
For this entry:
S15A1_HUMAN (SLC15A1)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Mooij MG,de Koning BE,Lindenbergh-Kortleve DJ,Simons-Oosterhuis Y,van Groen BD,Tibboel D,Samsom JN,de Wildt SN (2016) Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants., Drug Metab Dispos, 44, 1014-9. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Large intestine |
| Cell | Enterocytes |
| Notes |
S15A1_HUMAN (SLC15A1)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Mooij MG,de Koning BE,Lindenbergh-Kortleve DJ,Simons-Oosterhuis Y,van Groen BD,Tibboel D,Samsom JN,de Wildt SN (2016) Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants., Drug Metab Dispos, 44, 1014-9. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Large intestine |
| Cell | Goblet cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 13 | Cytoplasmic |
| 14 | 31 | Membrane |
| 32 | 53 | Extracellular |
| 54 | 73 | Membrane |
| 74 | 82 | Cytoplasmic |
| 83 | 103 | Membrane |
| 104 | 119 | Extracellular |
| 120 | 139 | Membrane |
| 140 | 164 | Cytoplasmic |
| 165 | 184 | Membrane |
| 185 | 199 | Extracellular |
| 200 | 219 | Membrane |
| 220 | 278 | Cytoplasmic |
| 279 | 297 | Membrane |
| 298 | 326 | Extracellular |
| 327 | 344 | Membrane |
| 345 | 360 | Cytoplasmic |
| 361 | 378 | Membrane |
| 379 | 587 | Extracellular |
| 588 | 607 | Membrane |
| 608 | 619 | Cytoplasmic |
| 620 | 639 | Membrane |
| 640 | 648 | Extracellular |
| 649 | 667 | Membrane |
| 668 | 708 | Cytoplasmic |
Phosphorylation
Glycosylation
| Position | Site resource | Glycan resource | PubMed link(s) |
|---|---|---|---|
| 404 | N-GlycoSiteAtlas | ||
| 439 | N-GlycoSiteAtlas | 22148984 , 24191733 , 24741114 , 24495048 , 26571101 | |
| 439 | PolarProtDb | 31844046 | |
| 509 | N-GlycoSiteAtlas | 24495048 | |
| 509 | PolarProtDb | 31844046 | |
| 514 | N-GlycoSiteAtlas | 26571101 | |
| 514 | PolarProtDb | 31844046 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | MFS_trans_sf |
| InterPro | Oligopep_transport |
| InterPro | POT_fam |
| InterPro | PTR2_symporter_CS |
| Pfam | PTR2 |