PolarProtDb

Gene name

PTPRO (GLEPP1,Ptpn15,PTPU2)

Experiment(s)

For this entry:

PTPRO_MOUSE (PTPRO)

Species	Mus musculus
Localization	Apical plasma membrane
Reference	Wang R,St John PL,Kretzler M,Wiggins RC,Abrahamson DR (2000) Molecular cloning, expression, and distribution of glomerular epithelial protein 1 in developing mouse kidney., Kidney Int, 57, 1847-59. [PubMed] [DOI]
Evidence level	Antibody staining
Organ	Kidney
Cell	Podocytes
Notes

For ortholog entries:

Q62797_RAT

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).

CCTOP topology prediction

Start	End	Localisation
1	30	Signal peptide
31	830	Extracellular
831	854	Membrane
855	1226	Cytoplasmic

Phosphorylation

Position	Resource
8	51636739
613	26419979
614	26419983
667	25751034
668	25751042
869	31907542
875	12738824
1220	14312604

Glycosylation

Position	Site resource	Glycan resource	PubMed link(s)
722	Glyconnect	$WURCS=2.0/2,7,6/[axxxxh-1x_1-5_2*NCC/3=O][axxxxh-1x_1-5]/1-1-2-2-2-2-2/a?\|b?\|c?\|d?\|e?\|f?\|g?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?_a?\|b?\|c?\|d?\|e?\|f?\|g?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?_a?\|b?\|c?\|d?\|e?\|f?\|g?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?_a?\|b?\|c?\|d?\|e?\|f?\|g?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?_a?\|b?\|c?\|d?\|e?\|f?\|g?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?_a?\|b?\|c?\|d?\|e?\|f?\|g?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?$	30899004
722	Glyconnect	$WURCS=2.0/2,8,7/[axxxxh-1x_1-5_2*NCC/3=O][axxxxh-1x_1-5]/1-1-2-2-2-2-2-2/a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?$	30899004

Family and domain data

Database	Domain/Family name
InterPro	FN3_dom
InterPro	FN3_sf
InterPro	Ig-like_fold
InterPro	Prot-tyrosine_phosphatase-like
InterPro	PTPase_domain
InterPro	PTPRO
InterPro	Tyr_Pase_AS
InterPro	Tyr_Pase_cat
InterPro	TYR_PHOSPHATASE_dom
Pfam	fn3
Pfam	Y_phosphatase