Gene name
PTPRJ (DEP1)
Experiment(s)
For this entry:
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 35 | Signal peptide |
| 36 | 972 | Extracellular |
| 973 | 994 | Membrane |
| 995 | 1337 | Cytoplasmic |
Phosphorylation
Glycosylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | FN3_dom |
| InterPro | FN3_sf |
| InterPro | Ig-like_fold |
| InterPro | Prot-tyrosine_phosphatase-like |
| InterPro | PTPase_domain |
| InterPro | PTPRJ_TM |
| InterPro | Tyr_Pase_AS |
| InterPro | Tyr_Pase_cat |
| InterPro | TYR_PHOSPHATASE_dom |
| Pfam | fn3 |
| Pfam | PTP_tm |
| Pfam | Y_phosphatase |
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| ERBB2_HUMAN | 2 | 19167335 |
| GHR_HUMAN | 2 | 19167335 |
| FLT3_HUMAN | 3 | 23650535 |
| TIE2_HUMAN | 2 | 19167335 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.