Gene name
PTPRJ (DEP1)
Experiment(s)
For this entry:
F1P983_CANLF (PTPRJ)
| Species | Canis lupus familiaris |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Tan B,Yatim SMJM,Peng S,Gunaratne J,Hunziker W,Ludwig A (2020) The Mammalian Crumbs Complex Defines a Distinct Polarity Domain Apical of Epithelial Tight Junctions., Curr Biol, 30, 2791-2804.e6. [PubMed] [DOI] |
| Evidence level | Large-scale proteomics |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 863 | Extracellular |
| 864 | 885 | Membrane |
| 886 | 1228 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | FN3_dom |
| InterPro | FN3_sf |
| InterPro | Ig-like_fold |
| InterPro | Prot-tyrosine_phosphatase-like |
| InterPro | PTPase_domain |
| InterPro | PTPRJ_TM |
| InterPro | Tyr_Pase_AS |
| InterPro | Tyr_Pase_cat |
| InterPro | TYR_PHOSPHATASE_dom |
| Pfam | PTP_tm |
| Pfam | Y_phosphatase |