Gene name
SLC51A (RGD1311100_predicted,OSTA,OSTalpha)
Experiment(s)
For this entry:
OSTA_MOUSE (SLC51A)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Dawson PA,Hubbert M,Haywood J,Craddock AL,Zerangue N,Christian WV,Ballatori N (2005) The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter., J Biol Chem, 280, 6960-8. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes | Part of a heteromeric OSTA-OSTB complex |
OSTA_MOUSE (SLC51A)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Ballatori N,Christian WV,Lee JY,Dawson PA,Soroka CJ,Boyer JL,Madejczyk MS,Li N (2005) OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia., Hepatology, 42, 1270-9. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes |
OSTA_MOUSE (SLC51A)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Ballatori N,Christian WV,Lee JY,Dawson PA,Soroka CJ,Boyer JL,Madejczyk MS,Li N (2005) OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia., Hepatology, 42, 1270-9. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 48 | Extracellular |
| 49 | 69 | Membrane |
| 70 | 87 | Cytoplasmic |
| 88 | 108 | Membrane |
| 109 | 114 | Extracellular |
| 115 | 135 | Membrane |
| 136 | 181 | Cytoplasmic |
| 182 | 202 | Membrane |
| 203 | 218 | Extracellular |
| 219 | 240 | Membrane |
| 241 | 256 | Cytoplasmic |
| 257 | 277 | Membrane |
| 278 | 295 | Extracellular |
| 296 | 316 | Membrane |
| 317 | 340 | Cytoplasmic |
Phosphorylation
| Position | Resource |
|---|---|
| 330 | 1868283423 |
| 336 | 1868288894 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Ostalpha/TMEM184C |
| Pfam | Solute_trans_a |