Gene name
SLC51A (RGD1311100_predicted,OSTA,OSTalpha)
Experiment(s)
For this entry:
OSTA_HUMAN (SLC51A)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Ballatori N,Christian WV,Lee JY,Dawson PA,Soroka CJ,Boyer JL,Madejczyk MS,Li N (2005) OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia., Hepatology, 42, 1270-9. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes |
OSTA_HUMAN (SLC51A)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Ballatori N,Christian WV,Lee JY,Dawson PA,Soroka CJ,Boyer JL,Madejczyk MS,Li N (2005) OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia., Hepatology, 42, 1270-9. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
OSTA_HUMAN (SLC51A)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Ballatori N,Christian WV,Lee JY,Dawson PA,Soroka CJ,Boyer JL,Madejczyk MS,Li N (2005) OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia., Hepatology, 42, 1270-9. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Liver |
| Cell | Hepatocytes |
| Notes |
OSTA_HUMAN (SLC51A)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Ballatori N,Christian WV,Lee JY,Dawson PA,Soroka CJ,Boyer JL,Madejczyk MS,Li N (2005) OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia., Hepatology, 42, 1270-9. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Liver |
| Cell | Bile duct cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 48 | Extracellular |
| 49 | 69 | Membrane |
| 70 | 87 | Cytoplasmic |
| 88 | 108 | Membrane |
| 109 | 117 | Extracellular |
| 118 | 138 | Membrane |
| 139 | 181 | Cytoplasmic |
| 182 | 202 | Membrane |
| 203 | 217 | Extracellular |
| 218 | 238 | Membrane |
| 239 | 256 | Cytoplasmic |
| 257 | 277 | Membrane |
| 278 | 295 | Extracellular |
| 296 | 316 | Membrane |
| 317 | 340 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Ostalpha/TMEM184C |
| Pfam | Solute_trans_a |
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| DJC30_HUMAN | 3 | 32296183 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.