Gene name
Slc34a2 (Npt2b)
Experiment(s)
For this entry:
NPT2B_RAT (Slc34a2)
| Species | Rattus norvegicus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Giral H,Cranston D,Lanzano L,Caldas Y,Sutherland E,Rachelson J,Dobrinskikh E,Weinman EJ,Doctor RB,Gratton E,Levi M (2012) NHE3 regulatory factor 1 (NHERF1) modulates intestinal sodium-dependent phosphate transporter (NaPi-2b) expression in apical microvilli., J Biol Chem, 287, 35047-56. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 96 | Cytoplasmic |
| 97 | 118 | Membrane |
| 119 | 138 | Extracellular |
| 139 | 157 | Membrane |
| 158 | 218 | Cytoplasmic |
| 219 | 239 | Membrane |
| 240 | 362 | Extracellular |
| 363 | 384 | Membrane |
| 385 | 408 | Cytoplasmic |
| 409 | 430 | Membrane |
| 431 | 432 | Extracellular |
| 433 | 451 | Membrane |
| 452 | 453 | Cytoplasmic |
| 454 | 475 | Membrane |
| 476 | 486 | Extracellular |
| 487 | 506 | Membrane |
| 507 | 526 | Cytoplasmic |
| 527 | 547 | Membrane |
| 548 | 553 | Extracellular |
| 554 | 575 | Membrane |
| 576 | 695 | Cytoplasmic |
Phosphorylation
| Position | Resource |
|---|---|
| 27 | 36704112 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Na/Pi_transpt |
| InterPro | Na/Pi_transpt_2B |
| Pfam | Na_Pi_cotrans |