Gene name

SLC16A8 (Mct3)

Experiment(s)

For this entry:
MOT3_RAT (SLC16A8)
Species Rattus norvegicus
Localization Basolateral plasma membrane
Reference Philp NJ,Yoon H,Grollman EF (1998) Monocarboxylate transporter MCT1 is located in the apical membrane and MCT3 in the basal membrane of rat RPE., Am J Physiol, 274, R1824-8.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Retina
Cell Pigment epithel cells
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 15 Cytoplasmic
16 36 Membrane
37 57 Extracellular
58 78 Membrane
79 85 Cytoplasmic
86 105 Membrane
106 112 Extracellular
113 134 Membrane
135 143 Cytoplasmic
144 164 Membrane
165 173 Extracellular
174 194 Membrane
195 228 Cytoplasmic
229 250 Membrane
251 263 Extracellular
264 285 Membrane
286 294 Cytoplasmic
295 315 Membrane
316 320 Extracellular
321 341 Membrane
342 355 Cytoplasmic
356 375 Membrane
376 387 Extracellular
388 409 Membrane
410 492 Cytoplasmic
Eukaryotic Linear Motif (ELM)
Start End Sequence Motif
5 8 GPRR TRG_ER_diArg_1

Family and domain data

Database Domain/Family name
InterPro MCT
InterPro MCT3
InterPro MFS
InterPro MFS_dom
InterPro MFS_trans_sf
Pfam MFS_1

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