Gene name
Slc16a1 (Mct1)
Experiment(s)
For this entry:
MOT1_RAT (Slc16a1)
Species | Rattus norvegicus |
---|---|
Localization | Non polar membrane |
Reference |
Roberts LM,Black DS,Raman C,Woodford K,Zhou M,Haggerty JE,Yan AT,Cwirla SE,Grindstaff KK (2008) Subcellular localization of transporters along the rat blood-brain barrier and blood-cerebral-spinal fluid barrier by in vivo biotinylation., Neuroscience, 155, 423-38. [PubMed] [DOI] |
Evidence level | Antibody staining |
Organ | Vessels |
Cell | Brain capillary endothelial cells |
Notes |
MOT1_RAT (Slc16a1)
Species | Rattus norvegicus |
---|---|
Localization | Apical plasma membrane |
Reference |
Philp NJ,Yoon H,Grollman EF (1998) Monocarboxylate transporter MCT1 is located in the apical membrane and MCT3 in the basal membrane of rat RPE., Am J Physiol, 274, R1824-8. [PubMed] [DOI] |
Evidence level | Antibody staining |
Organ | Retina |
Cell | Pigment epithel cells |
Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start | End | Localisation |
---|---|---|
1 | 16 | Cytoplasmic |
17 | 37 | Membrane |
38 | 57 | Extracellular |
58 | 79 | Membrane |
80 | 86 | Cytoplasmic |
87 | 106 | Membrane |
107 | 111 | Extracellular |
112 | 133 | Membrane |
134 | 143 | Cytoplasmic |
144 | 165 | Membrane |
166 | 175 | Extracellular |
176 | 195 | Membrane |
196 | 255 | Cytoplasmic |
256 | 277 | Membrane |
278 | 290 | Extracellular |
291 | 312 | Membrane |
313 | 321 | Cytoplasmic |
322 | 342 | Membrane |
343 | 346 | Extracellular |
347 | 368 | Membrane |
369 | 382 | Cytoplasmic |
383 | 402 | Membrane |
403 | 414 | Extracellular |
415 | 436 | Membrane |
437 | 494 | Cytoplasmic |
Phosphorylation
Family and domain data
Interactions
With (links to EBI) | #Exp | PubMed links |
---|---|---|
BASI_HUMAN | 4 | 17127621 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.