Gene name
Kcnk6 (LOC100909725,TOSS,TWIK2)
Experiment(s)
For this entry:
| Species |
Homo sapiens |
| Localization |
Apical plasma membrane |
| Reference |
Zhao KQ,Xiong G,Wilber M,Cohen NA,Kreindler JL (2012) A role for two-pore K⁺ channels in modulating Na⁺ absorption and Cl⁻ secretion in normal human bronchial epithelial cells., Am J Physiol Lung Cell Mol Physiol, 302, L4-L12.
[PubMed]
[DOI] |
| Evidence level |
Antibody staining |
| Organ |
Lung |
| Cell |
Airway epithel cells |
| Notes |
|
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start |
End |
Localisation |
| 1 |
5 |
Extracellular |
| 6 |
26 |
Membrane |
| 27 |
92 |
Cytoplasmic |
| 93 |
113 |
Membrane |
| 114 |
121 |
Extracellular |
| 122 |
142 |
Membrane |
| 143 |
170 |
Cytoplasmic |
| 171 |
192 |
Membrane |
| 193 |
200 |
Extracellular |
| 201 |
221 |
Membrane |
| 222 |
235 |
Cytoplasmic |
| 236 |
256 |
Membrane |
| 257 |
313 |
Extracellular |
Phosphorylation
Family and domain data