Gene name

SLC16A3 (MCT4,Mct3)

Experiment(s)

For this entry:
J9NVM8_CANLF (SLC16A3)
Species Canis lupus familiaris
Localization Basolateral plasma membrane
Reference Deora AA,Philp N,Hu J,Bok D,Rodriguez-Boulan E (2005) Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epithelia., Proc Natl Acad Sci U S A, 102, 16245-50.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Kidney
Cell MDCK cells (distal tubule)
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 20 Cytoplasmic
21 41 Membrane
42 60 Extracellular
61 82 Membrane
83 88 Cytoplasmic
89 108 Membrane
109 113 Extracellular
114 134 Membrane
135 146 Cytoplasmic
147 167 Membrane
168 176 Extracellular
177 197 Membrane
198 228 Cytoplasmic
229 250 Membrane
251 263 Extracellular
264 285 Membrane
286 294 Cytoplasmic
295 315 Membrane
316 320 Extracellular
321 341 Membrane
342 352 Cytoplasmic
353 373 Membrane
374 386 Extracellular
387 408 Membrane
409 464 Cytoplasmic

Family and domain data

Database Domain/Family name
InterPro MCT
InterPro MCT4
InterPro MFS
InterPro MFS_dom
InterPro MFS_trans_sf
Pfam MFS_1

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