Gene name
SLC2A9 (Glut9)
Experiment(s)
For this entry:
GTR9_MOUSE (SLC2A9)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Tomioka NH,Tamura Y,Takada T,Shibata S,Suzuki H,Uchida S,Hosoyamada M (2016) Immunohistochemical and in situ hybridization study of urate transporters GLUT9/URATv1, ABCG2, and URAT1 in the murine brain., Fluids Barriers CNS, 13, 22. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Vessels |
| Cell | Brain capillary endothelial cells |
| Notes |
GTR9_MOUSE (SLC2A9)
| Species | Mus musculus |
|---|---|
| Localization | Non polar membrane |
| Reference |
Tomioka NH,Tamura Y,Takada T,Shibata S,Suzuki H,Uchida S,Hosoyamada M (2016) Immunohistochemical and in situ hybridization study of urate transporters GLUT9/URATv1, ABCG2, and URAT1 in the murine brain., Fluids Barriers CNS, 13, 22. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Brain ventricle |
| Cell | Ependymal cells |
| Notes | Does not seem to be expressed in ependymal cells of the choroid plexus |
GTR9_MOUSE (SLC2A9)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Keembiyehetty C,Augustin R,Carayannopoulos MO,Steer S,Manolescu A,Cheeseman CI,Moley KH (2006) Mouse glucose transporter 9 splice variants are expressed in adult liver and kidney and are up-regulated in diabetes., Mol Endocrinol, 20, 686-97. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Liver |
| Cell | Hepatocytes |
| Notes | Both the long and the short isoforms are basolateral - opposing to the human ortholog |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 39 | Cytoplasmic |
| 40 | 61 | Membrane |
| 62 | 91 | Extracellular |
| 92 | 112 | Membrane |
| 113 | 119 | Cytoplasmic |
| 120 | 139 | Membrane |
| 140 | 146 | Extracellular |
| 147 | 167 | Membrane |
| 168 | 181 | Cytoplasmic |
| 182 | 201 | Membrane |
| 202 | 213 | Extracellular |
| 214 | 233 | Membrane |
| 234 | 298 | Cytoplasmic |
| 299 | 320 | Membrane |
| 321 | 336 | Extracellular |
| 337 | 356 | Membrane |
| 357 | 363 | Cytoplasmic |
| 364 | 382 | Membrane |
| 383 | 394 | Extracellular |
| 395 | 416 | Membrane |
| 417 | 432 | Cytoplasmic |
| 433 | 454 | Membrane |
| 455 | 460 | Extracellular |
| 461 | 478 | Membrane |
| 479 | 538 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | MFS_dom |
| InterPro | MFS_sugar_transport-like |
| InterPro | MFS_trans_sf |
| InterPro | Sugar/inositol_transpt |
| InterPro | Sugar_transporter_CS |
| Pfam | Sugar_tr |