Gene name

SLC2A9 (Glut9)

Experiment(s)

For this entry:
GTR9_HUMAN (SLC2A9)
Species Homo sapiens
Localization Basolateral plasma membrane
Reference Bibee KP,Augustin R,Gazit V,Moley KH (2013) The apical sorting signal for human GLUT9b resides in the N-terminus., Mol Cell Biochem, 376, 163-73.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Kidney
Cell MDCK cells (distal tubule)
Notes The shorter isoform carries a unique apical determinant (MKLSKKDRGEDEESDSAKKKL) on its N-terminus
GTR9_HUMAN (SLC2A9)
Species Homo sapiens
Localization Basolateral plasma membrane
Reference Uehara I,Kimura T,Tanigaki S,Fukutomi T,Sakai K,Shinohara Y,Ichida K,Iwashita M,Sakurai H (2014) Paracellular route is the major urate transport pathway across the blood-placental barrier., Physiol Rep, 2, .
[PubMed] [DOI]
Evidence level Antibody staining
Organ Placenta
Cell Trophoblast cells
Notes The short isoform is apical in the same tissue
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 58 Cytoplasmic
59 80 Membrane
81 110 Extracellular
111 132 Membrane
133 138 Cytoplasmic
139 158 Membrane
159 165 Extracellular
166 186 Membrane
187 200 Cytoplasmic
201 219 Membrane
220 232 Extracellular
233 252 Membrane
253 317 Cytoplasmic
318 337 Membrane
338 353 Extracellular
354 375 Membrane
376 382 Cytoplasmic
383 401 Membrane
402 414 Extracellular
415 436 Membrane
437 451 Cytoplasmic
452 473 Membrane
474 479 Extracellular
480 499 Membrane
500 540 Cytoplasmic
Phosphorylation
Position Resource
9 34501191
502 5275749
506 5275754
515 34502379
Glycosylation
Position Site resource Glycan resource PubMed link(s)
90 N-GlycoSiteAtlas 24495048 , 26571101
90 PolarProtDb 31844046

Family and domain data

Database Domain/Family name
InterPro MFS_dom
InterPro MFS_sugar_transport-like
InterPro MFS_trans_sf
InterPro Sugar/inositol_transpt
InterPro Sugar_transporter_CS
Pfam Sugar_tr

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