Gene name
Slc2a2 (Glut2)
Experiment(s)
For this entry:
GTR2_MOUSE (Slc2a2)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Keembiyehetty C,Augustin R,Carayannopoulos MO,Steer S,Manolescu A,Cheeseman CI,Moley KH (2006) Mouse glucose transporter 9 splice variants are expressed in adult liver and kidney and are up-regulated in diabetes., Mol Endocrinol, 20, 686-97. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Liver |
| Cell | Hepatocytes |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 11 | Cytoplasmic |
| 12 | 31 | Membrane |
| 32 | 97 | Extracellular |
| 98 | 117 | Membrane |
| 118 | 124 | Cytoplasmic |
| 125 | 144 | Membrane |
| 145 | 151 | Extracellular |
| 152 | 172 | Membrane |
| 173 | 186 | Cytoplasmic |
| 187 | 206 | Membrane |
| 207 | 218 | Extracellular |
| 219 | 238 | Membrane |
| 239 | 303 | Cytoplasmic |
| 304 | 323 | Membrane |
| 324 | 339 | Extracellular |
| 340 | 359 | Membrane |
| 360 | 366 | Cytoplasmic |
| 367 | 385 | Membrane |
| 386 | 398 | Extracellular |
| 399 | 420 | Membrane |
| 421 | 434 | Cytoplasmic |
| 435 | 456 | Membrane |
| 457 | 463 | Extracellular |
| 464 | 483 | Membrane |
| 484 | 523 | Cytoplasmic |
Phosphorylation
Glycosylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Glc_transpt_2 |
| InterPro | MFS_dom |
| InterPro | MFS_sugar_transport-like |
| InterPro | MFS_trans_sf |
| InterPro | Sugar/inositol_transpt |
| InterPro | Sugar_transporter_CS |
| Pfam | Sugar_tr |