Gene name
Slc2a2 (Glut2)
Experiment(s)
For this entry:
GTR2_HUMAN (Slc2a2)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Inukai K,Shewan AM,Pascoe WS,Katayama S,James DE,Oka Y (2004) Carboxy terminus of glucose transporter 3 contains an apical membrane targeting domain., Mol Endocrinol, 18, 339-49. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 11 | Cytoplasmic |
| 12 | 33 | Membrane |
| 34 | 98 | Extracellular |
| 99 | 118 | Membrane |
| 119 | 125 | Cytoplasmic |
| 126 | 145 | Membrane |
| 146 | 152 | Extracellular |
| 153 | 173 | Membrane |
| 174 | 187 | Cytoplasmic |
| 188 | 207 | Membrane |
| 208 | 219 | Extracellular |
| 220 | 239 | Membrane |
| 240 | 304 | Cytoplasmic |
| 305 | 324 | Membrane |
| 325 | 340 | Extracellular |
| 341 | 360 | Membrane |
| 361 | 367 | Cytoplasmic |
| 368 | 386 | Membrane |
| 387 | 399 | Extracellular |
| 400 | 421 | Membrane |
| 422 | 436 | Cytoplasmic |
| 437 | 458 | Membrane |
| 459 | 464 | Extracellular |
| 465 | 484 | Membrane |
| 485 | 524 | Cytoplasmic |
Phosphorylation
| Position | Resource |
|---|---|
| 523 | 467949 |
Glycosylation
| Position | Site resource | Glycan resource | PubMed link(s) |
|---|---|---|---|
| 62 | N-GlycoSiteAtlas | 24495048 | |
| 69 | UniCarbKB |
![WURCS=2.0/2,2,1/[uxxxxh_2*NCC/3=O][uxxxxh]/1-2/a?|b?}-{a?|b?](data:image/png;base64,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)
|
30459171 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Glc_transpt_2 |
| InterPro | MFS_dom |
| InterPro | MFS_sugar_transport-like |
| InterPro | MFS_trans_sf |
| InterPro | Sugar/inositol_transpt |
| InterPro | Sugar_transporter_CS |
| Pfam | Sugar_tr |