Gene name
FBLN1
Experiment(s)
For this entry:
FBLN1_HUMAN (FBLN1)
Species | Homo sapiens |
---|---|
Localization | Basolateral plasma membrane |
Reference |
Touzelet O,Broadbent L,Armstrong SD,Aljabr W,Cloutman-Green E,Power UF,Hiscox JA (2020) The Secretome Profiling of a Pediatric Airway Epithelium Infected with hRSV Identified Aberrant Apical/Basolateral Trafficking and Novel Immune Modulating (CXCL6, CXCL16, CSF3) and Antiviral (CEACAM1) Proteins., Mol Cell Proteomics, 19, 793-807. [PubMed] [DOI] |
Evidence level | Large-scale proteomics |
Organ | Lung |
Cell | Airway epithel cells |
Notes | Only mock-transfected cells were considered |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start | End | Localisation |
---|---|---|
1 | 703 | Extracellular |
Phosphorylation
Glycosylation
Position | Site resource | Glycan resource | PubMed link(s) |
---|---|---|---|
98 | Glyconnect | 29741879 | |
98 | UniProtKB | 19139490 | |
98 | UniPep | ||
98 | PolarProtDb | 31844046 | |
98 | N-GlycoSiteAtlas | 26571101 | |
98 | dbPTM | 19139490 | |
98 | GPTwiki | ||
98 | Glyconnect | 29741879 , 29671580 | |
98 | Glyconnect | 29741879 | |
98 | Glyconnect | 29741879 | |
98 | Glyconnect | 29741879 | |
98 | Glyconnect | 29741879 | |
98 | UniCarbKB | 29671580 | |
489 | UniCarbKB | 30459171 | |
535 | UniPep | ||
535 | N-GlycoSiteAtlas | 24495048 | |
535 | Glyconnect | 29741879 | |
535 | Glyconnect | 29741879 | |
539 | UniPep | ||
539 | N-GlycoSiteAtlas | 24495048 |
Family and domain data
Database | Domain/Family name |
---|---|
InterPro | Anaphylatoxin/fibulin |
InterPro | cEGF |
InterPro | EGF-like_Ca-bd_dom |
InterPro | EGF-like_dom |
InterPro | EGF-type_Asp/Asn_hydroxyl_site |
InterPro | EGF_Ca-bd_CS |
InterPro | Fibulin-1 |
InterPro | Growth_fac_rcpt_cys_sf |
Pfam | cEGF |
Pfam | EGF_CA |
Interactions
With (links to EBI) | #Exp | PubMed links |
---|---|---|
1433T_HUMAN | 2 | 21988832 |
SMAD3_HUMAN | 2 | 21988832 |
ATN1_HUMAN | 2 | 16713569 |
NLGN3_HUMAN | 2 | 25464930 |
APOA1_HUMAN | 2 | 21988832 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.