Gene name
Slc1a1 (Eaac1,Eaat3,ECO:0000303|PubMed:9011753})
Experiment(s)
For this entry:
EAA3_RAT (Slc1a1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Shayakul C,Kanai Y,Lee WS,Brown D,Rothstein JD,Hediger MA (1997) Localization of the high-affinity glutamate transporter EAAC1 in rat kidney., Am J Physiol, 273, F1023-9. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 22 | Cytoplasmic |
| 23 | 38 | Membrane |
| 39 | 51 | Extracellular |
| 52 | 73 | Membrane |
| 74 | 100 | Cytoplasmic |
| 101 | 116 | Membrane |
| 117 | 152 | Extracellular |
| 153 | 171 | Membrane |
| 172 | 173 | Cytoplasmic |
| 174 | 192 | Membrane |
| 193 | 194 | Extracellular |
| 195 | 218 | Membrane |
| 219 | 246 | Cytoplasmic |
| 247 | 268 | Membrane |
| 269 | 281 | Extracellular |
| 282 | 303 | Membrane |
| 304 | 360 | Cytoplasmic |
| 361 | 376 | Membrane |
| 377 | 393 | Extracellular |
| 394 | 409 | Membrane |
| 410 | 411 | Cytoplasmic |
| 412 | 427 | Membrane |
| 428 | 439 | Extracellular |
| 440 | 455 | Membrane |
| 456 | 523 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Na-dicarboxylate_symporter |
| InterPro | Na-dicarboxylate_symporter_CS |
| InterPro | Na:dicarbo_symporter_sf |
| Pfam | SDF |