Gene name
SLC1A2 (EAAT2,GLT1)
Experiment(s)
For this entry:
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 44 | Cytoplasmic |
| 45 | 66 | Membrane |
| 67 | 87 | Extracellular |
| 88 | 108 | Membrane |
| 109 | 119 | Cytoplasmic |
| 120 | 141 | Membrane |
| 142 | 237 | Extracellular |
| 238 | 258 | Membrane |
| 259 | 278 | Cytoplasmic |
| 279 | 300 | Membrane |
| 301 | 316 | Extracellular |
| 317 | 338 | Membrane |
| 339 | 386 | Cytoplasmic |
| 387 | 414 | Membrane |
| 415 | 430 | Extracellular |
| 431 | 458 | Membrane |
| 459 | 572 | Cytoplasmic |
Phosphorylation
Glycosylation
| Position | Site resource | Glycan resource | PubMed link(s) |
|---|---|---|---|
| 205 | Glyconnect |
|
30899004 |
| 205 | Glyconnect |
|
30899004 |
| 205 | PolarProtDb |
|
30899004 |
| 205 | Glyconnect |
|
30899004 |
| 205 | Glyconnect |
|
30899004 |
| 205 | Glyconnect |
|
30899004 |
| 205 | Glyconnect |
|
30899004 |
| 205 | Glyconnect |
|
|
| 205 | Glyconnect |
|
30899004 |
| 205 | Glyconnect |
|
30899004 |
| 205 | Glyconnect |
|
30899004 |
| 205 | Glyconnect |
|
30899004 |
| 205 | Glyconnect |
|
30899004 |
| 215 | Glyconnect |
|
30899004 |
| 215 | Glyconnect |
|
30899004 |
| 215 | Glyconnect |
|
30899004 |
| 215 | Glyconnect |
|
30899004 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Na-dicarboxylate_symporter |
| InterPro | Na-dicarboxylate_symporter_CS |
| InterPro | Na:dicarbo_symporter_sf |
| Pfam | SDF |
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| DLG4_MOUSE | 3 | 19455133 , 28671696 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.