Gene name
SLC1A2 (EAAT2,GLT1)
Experiment(s)
For this entry:
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start | End | Localisation |
---|---|---|
1 | 44 | Cytoplasmic |
45 | 66 | Membrane |
67 | 87 | Extracellular |
88 | 108 | Membrane |
109 | 119 | Cytoplasmic |
120 | 141 | Membrane |
142 | 237 | Extracellular |
238 | 258 | Membrane |
259 | 278 | Cytoplasmic |
279 | 300 | Membrane |
301 | 316 | Extracellular |
317 | 338 | Membrane |
339 | 386 | Cytoplasmic |
387 | 414 | Membrane |
415 | 430 | Extracellular |
431 | 458 | Membrane |
459 | 572 | Cytoplasmic |
Phosphorylation
Glycosylation
Position | Site resource | Glycan resource | PubMed link(s) |
---|---|---|---|
205 | Glyconnect | 30899004 | |
205 | Glyconnect | 30899004 | |
205 | PolarProtDb | 30899004 | |
205 | Glyconnect | 30899004 | |
205 | Glyconnect | 30899004 | |
205 | Glyconnect | 30899004 | |
205 | Glyconnect | 30899004 | |
205 | Glyconnect | ||
205 | Glyconnect | 30899004 | |
205 | Glyconnect | 30899004 | |
205 | Glyconnect | 30899004 | |
205 | Glyconnect | 30899004 | |
205 | Glyconnect | 30899004 | |
215 | Glyconnect | 30899004 | |
215 | Glyconnect | 30899004 | |
215 | Glyconnect | 30899004 | |
215 | Glyconnect | 30899004 |
Family and domain data
Database | Domain/Family name |
---|---|
InterPro | Na-dicarboxylate_symporter |
InterPro | Na-dicarboxylate_symporter_CS |
InterPro | Na:dicarbo_symporter_sf |
Pfam | SDF |
Interactions
With (links to EBI) | #Exp | PubMed links |
---|---|---|
DLG4_MOUSE | 3 | 19455133 , 28671696 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.