Gene name

Cst3

Experiment(s)

For this entry:
CYTC_HUMAN (Cst3)
Species Homo sapiens
Localization Basolateral plasma membrane
Reference Touzelet O,Broadbent L,Armstrong SD,Aljabr W,Cloutman-Green E,Power UF,Hiscox JA (2020) The Secretome Profiling of a Pediatric Airway Epithelium Infected with hRSV Identified Aberrant Apical/Basolateral Trafficking and Novel Immune Modulating (CXCL6, CXCL16, CSF3) and Antiviral (CEACAM1) Proteins., Mol Cell Proteomics, 19, 793-807.
[PubMed] [DOI]
Evidence level Large-scale proteomics
Organ Lung
Cell Airway epithel cells
Notes Only mock-transfected cells were considered
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 146 Extracellular
Phosphorylation
Position Resource
43 27446819
Glycosylation
Position Site resource Glycan resource PubMed link(s)
22 O-GlycoProteomDB
27 O-GlycoProteomDB
28 O-GlycoProteomDB

Family and domain data

Database Domain/Family name
InterPro Cystatin_dom
InterPro Prot_inh_cystat_CS
Pfam Cystatin

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