PolarProtDb

Gene name

SDF4 (CAB45)

Experiment(s)

For this entry:

CAB45_HUMAN (SDF4)

Species	Homo sapiens
Localization	Non polar membrane
Reference	Touzelet O,Broadbent L,Armstrong SD,Aljabr W,Cloutman-Green E,Power UF,Hiscox JA (2020) The Secretome Profiling of a Pediatric Airway Epithelium Infected with hRSV Identified Aberrant Apical/Basolateral Trafficking and Novel Immune Modulating (CXCL6, CXCL16, CSF3) and Antiviral (CEACAM1) Proteins., Mol Cell Proteomics, 19, 793-807. [PubMed] [DOI]
Evidence level	Large-scale proteomics
Organ	Lung
Cell	Airway epithel cells
Notes

For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).

CCTOP topology prediction

Start	End	Localisation
1	362	Extracellular

Phosphorylation

Position	Resource
99	31086887
158	34499647
162	23142340
173	27459767
193	460742
209	36126270
217	34500950
265	34500491
299	23142337
357	27459770

Glycosylation

Position	Site resource	Glycan resource	PubMed link(s)
40	N-GlycoSiteAtlas		22148984
108	dbPTM		55833783
108	O-GlycoProteomDB
108	PhosphoSitePlus
131	O-GlycoProteomDB
169	O-GlycoProteomDB
173	O-GlycoProteomDB
265	UniCarbKB	$WURCS=2.0/2,2,1/[uxxxxh_2*NCC/3=O][uxxxxh]/1-2/a?\|b?}-{a?\|b?$	30459171
265	O-GlycoProteomDB
265	PolarProtDb		29296958
343	PhosphoSitePlus
343	dbPTM		55826533
343	O-GlycoProteomDB
347	PhosphoSitePlus
347	PolarProtDb		29296958
347	dbPTM		55823899
347	O-GlycoProteomDB
349	PhosphoSitePlus
349	dbPTM		55823905
349	O-GlycoProteomDB
357	PhosphoSitePlus
357	PolarProtDb		29296958
357	dbPTM		54919541
357	O-GlycoProteomDB

Family and domain data

Database	Domain/Family name
InterPro	EF-hand-dom_pair
InterPro	EF_Hand_1_Ca_BS
InterPro	EF_hand_dom
Pfam	EF-hand_5
Pfam	EF-hand_7

Interactions

With (links to EBI)	#Exp	PubMed links
ILK_HUMAN	2	25852190 , 23455922
Q20MH8_I33A0	2	28169297
MYC_HUMAN	2	21150319 , 26496610
C5E527_9INFA	3	28169297
B4URF7_I33A0	3	28169297
RDRP_I34A1	4	28169297
Q77M19_MEASW	2	21911578
PB2_I34A1	3	28169297
ENV_HV1H2	3	22190034

Protein can be found in apical membrane, Protein can be found in basal membrane, Protein can be found both membranes, Localisation is unknown.