Gene name
BSG (RPE7)
Experiment(s)
For this entry:
BASI_HUMAN (BSG)
| Species | Homo sapiens |
|---|---|
| Localization | Non polar membrane |
| Reference |
Philp NJ,Wang D,Yoon H,Hjelmeland LM (2003) Polarized expression of monocarboxylate transporters in human retinal pigment epithelium and ARPE-19 cells., Invest Ophthalmol Vis Sci, 44, 1716-21. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Retina |
| Cell | ARPE-19 cells (pigment epithel cells) |
| Notes |
BASI_HUMAN (BSG)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Deora AA,Philp N,Hu J,Bok D,Rodriguez-Boulan E (2005) Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epithelia., Proc Natl Acad Sci U S A, 102, 16245-50. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Retina |
| Cell | Pigment epithel cells |
| Notes |
BASI_HUMAN (BSG)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Lobato-Álvarez JA,Roldán ML,López-Murillo TD,González-Ramírez R,Bonilla-Delgado J,Shoshani L (2016) The Apical Localization of Na<sup>+</sup>, K<sup>+</sup>-ATPase in Cultured Human Retinal Pigment Epithelial Cells Depends on Expression of the β<sub>2</sub> Subunit., Front Physiol, 7, 450. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Retina |
| Cell | Pigment epithel cells |
| Notes |
BASI_HUMAN (BSG)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Lobato-Álvarez JA,Roldán ML,López-Murillo TD,González-Ramírez R,Bonilla-Delgado J,Shoshani L (2016) The Apical Localization of Na<sup>+</sup>, K<sup>+</sup>-ATPase in Cultured Human Retinal Pigment Epithelial Cells Depends on Expression of the β<sub>2</sub> Subunit., Front Physiol, 7, 450. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Retina |
| Cell | ARPE-19 cells (pigment epithel cells) |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 21 | Signal peptide |
| 22 | 322 | Extracellular |
| 323 | 344 | Membrane |
| 345 | 385 | Cytoplasmic |
Phosphorylation
Glycosylation
| Position | Site resource | Glycan resource | PubMed link(s) |
|---|---|---|---|
| 144 | O-GlycoProteomDB | ||
| 145 | PhosphoSitePlus |
|
|
| 145 | dbPTM | 55824375 | |
| 145 | O-GlycoProteomDB | ||
| 160 | PolarProtDb |
|
29675740 |
| 160 | dbPTM | 12754519 , 19159218 , 19349973 | |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | N-GlycoSiteAtlas | 26571101 | |
| 160 | UniProtKB | 12754519 , 19159218 , 19349973 | |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | Glyconnect |
|
29741879 |
| 160 | PolarProtDb |
|
29675740 |
| 160 | PolarProtDb |
|
29675740 |
| 212 | UniCarbKB |
|
30459171 |
| 212 | O-GlycoProteomDB | ||
| 212 | UniCarbKB |
|
30459171 |
| 212 | PolarProtDb |
|
29296958 |
| 251 | PolarProtDb |
|
29296958 |
| 251 | O-GlycoProteomDB | ||
| 259 | O-GlycoProteomDB | ||
| 268 | dbPTM | 12754519 , 19159218 , 19349973 | |
| 268 | PolarProtDb |
|
29675740 |
| 268 | PolarProtDb |
|
29675740 |
| 268 | Glyconnect |
|
29741879 |
| 268 | Glyconnect |
|
29741879 |
| 268 | PolarProtDb |
|
29675740 |
| 268 | Glyconnect |
|
29741879 |
| 268 | PolarProtDb |
|
29675740 |
| 268 | PolarProtDb |
|
29675740 |
| 268 | N-GlycoSiteAtlas | 22148984 | |
| 268 | UniProtKB | 12754519 , 19159218 , 19349973 | |
| 268 | Glyconnect |
|
29741879 |
| 268 | PolarProtDb |
|
29675740 |
| 268 | PolarProtDb |
|
29675740 |
| 268 | UniCarbKB |
|
29741879 |
| 268 | Glyconnect |
|
29741879 |
| 268 | PolarProtDb |
|
29675740 |
| 268 | Glyconnect |
|
29741879 |
| 268 | Glyconnect |
|
29741879 |
| 268 | PolarProtDb |
|
29675740 |
| 268 | PolarProtDb |
|
29675740 |
| 268 | PolarProtDb |
|
29675740 |
| 268 | Glyconnect |
|
29741879 |
| 268 | PolarProtDb |
|
29675740 |
| 277 | O-GlycoProteomDB | ||
| 302 | N-GlycoSiteAtlas | 24495048 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Basigin-like |
| InterPro | Ig-like_dom |
| InterPro | Ig-like_dom_sf |
| InterPro | Ig-like_fold |
| InterPro | Ig_sub |
| InterPro | Ig_sub2 |
| InterPro | Neuroplastin/Basigin |
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| CFTR_HUMAN | 3 | 29924966 |
| POLG_ZIKVK | 2 | 30177828 |
| Q77M19_MEASW | 2 | 21911578 |
| MOT1_RAT | 4 | 17127621 |
| TGON2_HUMAN | 2 | 29568061 |
| OTUB1_HUMAN | 2 | 26752685 |
| CALX_HUMAN | 3 | 29568061 |
| SPIKE_SARS2 | 5 | unassigned2393 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.