Gene name
Atp8b1 (ATPIC,FIC1,PFIC)
Experiment(s)
For this entry:
AT8B1_MOUSE (Atp8b1)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
van Mil SW,van Oort MM,van den Berg IE,Berger R,Houwen RH,Klomp LW (2004) Fic1 is expressed at apical membranes of different epithelial cells in the digestive tract and is induced in the small intestine during postnatal development of mice., Pediatr Res, 56, 981-7. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Pancreas |
| Cell | Acinar cells |
| Notes |
AT8B1_MOUSE (Atp8b1)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
van Mil SW,van Oort MM,van den Berg IE,Berger R,Houwen RH,Klomp LW (2004) Fic1 is expressed at apical membranes of different epithelial cells in the digestive tract and is induced in the small intestine during postnatal development of mice., Pediatr Res, 56, 981-7. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 118 | Cytoplasmic |
| 119 | 136 | Membrane |
| 137 | 140 | Extracellular |
| 141 | 157 | Membrane |
| 158 | 339 | Cytoplasmic |
| 340 | 361 | Membrane |
| 362 | 385 | Extracellular |
| 386 | 406 | Membrane |
| 407 | 950 | Cytoplasmic |
| 951 | 971 | Membrane |
| 972 | 982 | Extracellular |
| 983 | 1003 | Membrane |
| 1004 | 1032 | Cytoplasmic |
| 1033 | 1053 | Membrane |
| 1054 | 1069 | Extracellular |
| 1070 | 1090 | Membrane |
| 1091 | 1099 | Cytoplasmic |
| 1100 | 1120 | Membrane |
| 1121 | 1142 | Extracellular |
| 1143 | 1163 | Membrane |
| 1164 | 1251 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | ATP8B1 |
| InterPro | ATPase_P-typ_cyto_dom_N |
| InterPro | ATPase_P-typ_P_site |
| InterPro | ATPase_P-typ_TM_dom_sf |
| InterPro | ATPase_P-typ_transduc_dom_A_sf |
| InterPro | HAD-like_sf |
| InterPro | HAD_sf |
| InterPro | P-type_ATPase_IV |
| InterPro | P-type_ATPase_N |
| InterPro | P_typ_ATPase |
| InterPro | P_typ_ATPase_c |
| Pfam | PhoLip_ATPase_C |
| Pfam | PhoLip_ATPase_N |