Gene name
Adgrg2 (Gpr64,HE6,TM7LN2,Me6)
Experiment(s)
For this entry:
AGRG2_MOUSE (Adgrg2)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Obermann H,Samalecos A,Osterhoff C,Schröder B,Heller R,Kirchhoff C (2003) HE6, a two-subunit heptahelical receptor associated with apical membranes of efferent and epididymal duct epithelia., Mol Reprod Dev, 64, 13-26. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Epididymis |
| Cell | Principal cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 17 | Cytoplasmic |
| 18 | 36 | Membrane |
| 37 | 621 | Extracellular |
| 622 | 645 | Membrane |
| 646 | 655 | Cytoplasmic |
| 656 | 675 | Membrane |
| 676 | 684 | Extracellular |
| 685 | 706 | Membrane |
| 707 | 729 | Cytoplasmic |
| 730 | 748 | Membrane |
| 749 | 778 | Extracellular |
| 779 | 802 | Membrane |
| 803 | 825 | Cytoplasmic |
| 826 | 845 | Membrane |
| 846 | 854 | Extracellular |
| 855 | 873 | Membrane |
| 874 | 1009 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | GPCR_2-like |
| InterPro | GPCR_2_secretin-like |
| InterPro | GPCR_2_secretin-like_CS |
| InterPro | GPS |
| Pfam | 7tm_2 |
| Pfam | GPS |